@article{Ammar_Gharib_Abd El-Aziz_Mahmoud_2023, title={Antiquorum Sensing and Antibiofilm Activities of Natural Products Against Bacillus cereus.}, volume={13}, url={https://advetresearch.com/index.php/AVR/article/view/1180}, abstractNote={<p><em>Bacillus cereus&nbsp;(B. cereus)</em> is a Gram-positive, spore-forming, and facultative anaerobic bacterium that is widely distributed in the environment. Commonly, <em>B. cereus</em> is a soil occupant and is generally isolated from food and food products. It is a human pathogen that causes two variant types of gastrointestinal diseases: diarrheal and emetic. Diseases caused by multidrug-resistant (MDR) bacteria are difficult to be treated. In addition, group of <em>B. cereus</em> has several virulence factors, which play their roles in pathogenesis, infectivity and its capability to form biofilms. <em>B. cereus</em> biofilm is grown on medical devices either abiotic or biotic surfaces. This biofilm avoids the bacteria from the effect of antibiotics and host immune system leading to chronic infections, persistence and mortalities. Thus, it is necessary to explore new antiquorum and antibiofilm agents better than the conventional therapy to eliminate the biofilm that reflect on controlling <em>B. cereus</em> infections. The present review will discuss <em>B. cereus</em> virulence attributes, antibiotic resistance profiles, and their ability to produce biofilm as well as its molecular regulation. The application of the antiquorum and antibiofilm approaches for infection control will be illustrated as well. Finally, we will spot the light on their consequence in food industry loses and human health risk.</p>}, number={2}, journal={Journal of Advanced Veterinary Research}, author={Ammar, Ahmed M. and Gharib, Ahlam A. and Abd El-Aziz, Norhan K. and Mahmoud, Rana Mohamed}, year={2023}, month={Apr.}, pages={295-304} }