Pharmacological Activities of Graviola (Annona muricata): A Mini-Review

Authors

  • Areej I. Salem Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt.
  • Hosny Abd El-Fadil Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt.
  • Nagaah Al-Sayed Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt.
  • Ahmed S. Alazzouni Department of Zoology, Faculty of Science, Helwan University, Egypt.
  • Sameh El-Nabtity Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44519, Egypt.

Abstract

Graviola (Annona muricata) is one major member of the plant family, Annonaceae. It is cultivated in the tropical zones, particularly in Central and South America. Graviola is worldwide known for its natural medicinal effects. In this regards, graviola extracts are used in the treatment of different kinds of cancers such as pancreatic, breast, prostate, lung, and blood cancers. The exact mechanisms behinds the anticancer effects of graviola are not clearly defined. However, it was assumed that graviola-induced apoptotic effects, necrosis, and modulation of the proliferation patterns of the cancer cells are major mechanistic effects of Graviola. Interestingly, graviola is also known for its other beneficial effects such as its antioxidant, anti-inflammatory, anti-rheumatic activities, and its wound healing effects. This mini review was undertaken to update and summarize the pharmacological activities of graviola.

Downloads

Published

2022-11-16

How to Cite

Salem, A. I. ., Abd El-Fadil, H. ., Al-Sayed, N. ., Alazzouni, A. S. ., & El-Nabtity, S. . (2022). Pharmacological Activities of Graviola (Annona muricata): A Mini-Review. Journal of Advanced Veterinary Research, 12(6), 785-790. Retrieved from https://advetresearch.com/index.php/AVR/article/view/1084

Issue

Vol. 12 No. 6 (2022): Special Issue (Veterinary Medicine and the Concept of One Health)

Section

Review Article

License

Copyright (c) 2022 Journal of Advanced Veterinary Research

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles under the following conditions: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0).

For more information: 

Attribution-NonCommercial-NoDerivs 
CC BY-NC-ND

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license