Potency of a combined Peste des petits ruminants and sheep pox freeze dried vaccine

Authors

  • Mohamed A. Saad Agricultural Research Center (ARC), Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Cairo, Egypt.
  • Magda A. Kalad Agricultural Research Center (ARC), Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Cairo, Egypt.
  • Afaf A. Abd El Wahab Agricultural Research Center (ARC), Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Cairo, Egypt.
  • Amira A. El Saied Agricultural Research Center (ARC), Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Cairo, Egypt.
  • Mohamed M. Youssef Agricultural Research Center (ARC), Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Cairo, Egypt.
  • Mohamed H. Kafafy Agricultural Research Center (ARC), Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Cairo, Egypt.
  • Dalia A.M. Abdel-Moety Agricultural Research Center (ARC), Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Cairo, Egypt.
  • Namaa A. Mohamed Agricultural Research Center (ARC), Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Cairo, Egypt.
  • Mohamed H. Khodeir Agricultural Research Center (ARC), Veterinary Serum and Vaccine Research Institute (VSVRI), Abbasia, Cairo, Egypt.

Keywords:

Peste des petits ruminants, Sheep pox , Lyophilization , Combined vaccine

Abstract

            Pest des petits ruminants (PPR) and sheep pox (SP) viruses represent a hazard facing the sheep population. The present work dealt with the preparation of a combined live attenuated vaccine that protects sheep against the two diseases. Successfully, combined Peste des petits ruminants and sheep pox freeze-dried vaccine was proven to sterile and be free from different aerobic and anaerobic bacteria, fungi, and mycoplasma contaminants; safe (as no atypical reaction either local or systemic in mice and sheep and did not affect close contact unvaccinated sheep) and potent (providing vaccinated sheep with high protective specific immunity against both causative viruses) for 6 months (the experimental period) suggesting that such immunity will remain to not less than one year. It could be recommended the use of such a vaccine to control the two diseases using one shot of vaccination saves time, effort, and cost. 

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Published

2024-05-05

How to Cite

Saad, M. A. ., Kalad, M. A. ., Abd El Wahab, A. A. ., El Saied, A. A. ., Youssef , M. M. ., Kafafy, M. H. ., Abdel-Moety, D. A. ., Mohamed, N. A. ., & Khodeir, M. H. . (2024). Potency of a combined Peste des petits ruminants and sheep pox freeze dried vaccine. Journal of Advanced Veterinary Research, 14(5), 780-784. Retrieved from https://advetresearch.com/index.php/AVR/article/view/1720

Issue

Vol. 14 No. 5 (2024): Special Issue (Veterinary Medicine and Food Safety Challenges)

Section

Original Research

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Copyright (c) 2024 Journal of Advanced Veterinary Research

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license