Effects of Enrofloxacin Administration on Semen Quality of Barbari bucks

Abstract

The present study was undertaken to study the effect of enrofloxacin administration on semen quality of Barbari buck. Six normal, healthy adult Barbari bucks (25-30 Kg) aged between 2 to 2.5 years were used as semen donors. The bucks were administered enrofloxacin at the dose of 5mg/kg body weight intra-muscularly daily for 7 days. From each buck biweekly eighteen semen ejaculates (1st to 18th) were collected and one sample (0th) from each buck was collected before administration of enrofloxacin, using a non-oestrous doe as dummy and investigated for semen quality parameters. There was no significant difference (P≥0.05) in seminal volume between different ejaculates. Mass motility decreased significantly (P≤0.01) and was lowest in 4th ejaculate as compared to mass motility prior to drug administration. Highest significant (P≤0.01) decrease in progressive motility was seen in 9th ejaculate as compared to progressive motility before drug administration. Sperm concentration decreased significantly (P≤0.01) and was found to be lowest in 4th ejaculate as compared to sperm concentration before enrofloxacin administration. Percent live spermatozoa decreased significantly (P≤0.01) and was found to be minmum in 12th ejaculate as compared to sperm concentration prior to drug administration. Highest significant increase (P≤ 0.01) in per cent head, mid-piece and tail abnormalities of spermatozoa was observed in 4th, 3rd and 6th ejaculate respectively following parentral administration of enrofloxacion as compared to ejaculate before drug administration. Following drug administration, the semen quality decreased progressively and then became slowly normal after 14th ejaculate.