Evaluation of The Economic Efficacy of Some Antimycotoxicosis Compounds on Production and Humoral Immunity in Broiler Chickens.

Abstract

Mycotoxicosis is an important problem in poultry industry causing global economic losses constituting a great threat. The present study was designed to investigate the ameliorative effects of four different antimycotoxicosis compounds (AMCs) against production, economic performance and humoral immunity induced by intoxication of dietary aflatoxin (AF) and/or ochratoxin (OT) in broiler chicks. Experiment (I), AF (23 ppb) and OT (17 ppb) were fed alone or mixed and in association with antimycotoxin feed additives, product A or B (1 and 0.5 g/kg feed), respectively. In experiment (II), the intoxicated chicks treated with antimycotoxin drugs, product C or D in drinking water (1ml/liter/3 successive days and 0.5 ml/liter/one day), respectively. Results revealed that chicks intoxicated with AF and/or OT showed significant (P<0.05) increase in feed conversion ratio (FCR) and mortality percentages (%) while the antibody titers against Newcastle disease (ND) virus were significantly (P<0.05) reduced. It is interesting to note that the adverse effects on FCR and mortality % were significantly (P<0.05) reduced in the single AF or OT contaminated diets with dietary supplementation of product A but in the mixed AF and OT contaminated diet, FCR were significantly (P<0.05) decreased with addition of product B. Also, product B showed significant (P<0.05) increase in the antibody titers against ND in all AF and/or OT contaminated groups. Moreover, the treatment of AF and/or OT intoxicated chicks with product C or D in the drinking water was reported significant (P<0.05) decrease in the mortality% and non-significant (P>0.05) change in FCR and ND antibody titers.