Focal Myasthenia Gravis in Two Dogs


  • Ayman Atiba
  • Chie Yoshida
  • Noriko Nakashima
  • Hiroshi Ueno
  • Yuji Uzuka


AChRs antibody; Dog; Megaesophagus; Myasthenia gravis; Pyridostigmine bromide


Two dogs were presented with history of regurgitation. Both dogs were diagnosed with focal myasthenia gravis (FMG). Thoracic radiography was consisted with megaesophagus. Acetylcholine receptors (AChRs) antibody titer was positive. Both dogs were treated with pyridostigmine bromide as sole treatment. One case rapidly resolved with the recovery of the esophagus, while the other case even the AChRs antibody titer was normalized after 60 days but the clinical remission was occurred after long time. This report suggested that clinical signs of FMG were resolved, but we can’t predict the time required, additionally, pyridostigmine bromide might be effective for palliation of symptoms.




How to Cite

Atiba, A., Yoshida, C., Nakashima, N., Ueno, H., & Uzuka, Y. (2014). Focal Myasthenia Gravis in Two Dogs. Journal of Advanced Veterinary Research, 4(3), 145-148. Retrieved from



Case Report