A Case of Giant Myxoid Liposarcoma in a Cow

Abstract

In this case, it was aimed to evaluate the immunohistochemical and histopathological examinations along with surgical intervention results of a myxoid liposarcoma in a ten-year-old, female hybrid cattle. During clinical examination, an elastic mass, approximately 35x30x30 cm in size, was detected in the right fossa paralumbal region. As a treatment, total extirpation of the mass under sedation and local infiltration anesthesia was performed. The sections were prepared from the extirpated mass tissues and stained with hematoxylin-eosin for histopathological examination. In addition they were labeled with S-100 antibody for immunohistochemical examination. Histopathologically, atypical stellate spindle-shaped tumour cells were seen in the stroma of hypocellular region and inlarge lipoid cells locally and also, around the numerous vessels with thin Wall character. In addition, it was determined that these cells reacted positively with S-100 antibody immunohistochemically. After the removal of the mass surgically, no recurrence was observed during 2 year follow up and it was learned that the general condition of the cattle was good. As a result, due to the rarity of the disease, it was concluded that reporting myxoid liposarcoma cases may contribute to future studies.