Pharmacological activities and medicinal uses of berberine: A review

Authors

  • Gamal Shams Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
  • Somia Abd Allah Biochemistry Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
  • Raghda Ezzat B.Sc. Faculty of Pharmacy, Zagazig University, Master of Pharmacology, Zagazig University, Egypt.

Keywords:

Berberine , Pharmacological Activities , Medicinal Uses

Abstract

Berberine (BBR) is an isoquinoline derivative alkaloid that has been identified from a variety of plant species including Cortex phellodendron (Huang bai), Hydrastis canadensis (goldenseal), and Rhizoma coptidis (Huanglian). A growing body of research has demonstrated that this chemical has a wide range of biological functions, including antioxidant and anti-inflammatory, anticancer, and anti-hyperglycemic properties. BBR has been proven in studies to reduce the production of inflammatory mediators such as TNF-, IL-1, IL-6, and IL-8. Furthermore, BBR appears to boost the cellular antioxidant defense mechanism by raising the activity of CAT, SOD, and GPx while reducing OS variables such as protein carbonyl (PC) content, MDA, and NO levels. This review threw light on the pharmacological activities and medicinal uses of BBR.

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Published

2024-02-09

How to Cite

Shams, G. ., Abd Allah, S. ., & Ezzat, R. . (2024). Pharmacological activities and medicinal uses of berberine: A review. Journal of Advanced Veterinary Research, 14(2), 330-334. Retrieved from https://advetresearch.com/index.php/AVR/article/view/1515

Issue

Vol. 14 No. 2 (2024): Special Issue (Veterinary Medicine and Food Safety Challenges)

Section

Review Article

License

Copyright (c) 2024 Journal of Advanced Veterinary Research

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license